[HTML][HTML] 3D tumor angiogenesis models: recent advances and challenges
SM Bhat, VA Badiger, S Vasishta, J Chakraborty… - Journal of Cancer …, 2021 - Springer
… the qualitative and quantitative expression of pro and anti-angiogenic molecules. As …
on tumor endothelial cell biology. Further, 3-dimensional (3D) cultures were also developed …
on tumor endothelial cell biology. Further, 3-dimensional (3D) cultures were also developed …
[HTML][HTML] In vitro 3D Systems to Model Tumor Angiogenesis and Interactions With Stromal Cells
N Brassard-Jollive, C Monnot, L Muller… - Frontiers in cell and …, 2020 - frontiersin.org
… to anti-cancer therapies such as anti-angiogenic, radio-, and … the impact of shear stress and
interstitial flow and growth factor … Endothelial cells are seeded on Cytodex beads (blue) and …
interstitial flow and growth factor … Endothelial cells are seeded on Cytodex beads (blue) and …
Establishment of a 3D model of tumor-driven angiogenesis to study the effects of anti-angiogenic drugs on pericyte recruitment
Y Qiu, N Wang, T Guo, S Liu, X Tang, Z Zhong… - Biomaterials …, 2021 - pubs.rsc.org
… In this study, we developed a microcarrier-based 3D model of tumor-driven angiogenesis
composed of endothelial cells, … for investigating the interactions between endothelial cells and …
composed of endothelial cells, … for investigating the interactions between endothelial cells and …
Anti-angiogenic agents—overcoming tumour endothelial cell anergy and improving immunotherapy outcomes
ZR Huinen, EJM Huijbers, JR van Beijnum… - Nature Reviews …, 2021 - nature.com
… how the angiogenesis-induced endothelial immune cell barrier … We developed in vivo
models to demonstrate that the … Upon interaction with tumour cells, T cells lose their ability to …
models to demonstrate that the … Upon interaction with tumour cells, T cells lose their ability to …
[HTML][HTML] Modeling the efficacy of different anti-angiogenic drugs on treatment of solid tumors using 3D computational modeling and machine learning
… of tumor cell proliferation and endothelial cell angiogenesis … on the three-dimensional
simulation of tumor growth, with … explicit knowledge of underlying interactions. While mathematical …
simulation of tumor growth, with … explicit knowledge of underlying interactions. While mathematical …
[HTML][HTML] … to evaluate the antiangiogenic potential of melatonin to neutralize the angiogenic effects of VEGF and breast cancer cells: CAM assay and 3D endothelial cell …
A Laborda-Illanes, L Sánchez-Alcoholado… - Biomedicine & …, 2023 - Elsevier
… study was to develop rapid, economic, high capacity and easy handling angiogenesis assays
to test the antiangiogenic effects … cancer cells interacts with VEGF receptors in endothelial …
to test the antiangiogenic effects … cancer cells interacts with VEGF receptors in endothelial …
The anti-angiogenic effect of atorvastatin loaded exosomes on glioblastoma tumor cells: An in vitro 3D culture model
… exposed to hypoxia and nutrient deficiency, leading to rapid tumor growth and metastasis. …
-tumor effects on glioblastoma cells through directly inhibiting endothelial cell angiogenesis …
-tumor effects on glioblastoma cells through directly inhibiting endothelial cell angiogenesis …
[HTML][HTML] In vitro modeling of solid tumor interactions with perfused blood vessels
… of a human umbilical vein endothelial cell (HUVEC)-lined, … , (2) promote angiogenesis, and
(3) facilitate the sprouting of tumor … For example, drug testing for anti-angiogenic therapies …
(3) facilitate the sprouting of tumor … For example, drug testing for anti-angiogenic therapies …
3D modeling in cancer studies
… the effects of cancer cell–microenvironment interactions on … angiogenesis of ECs and
invasion of cancer cells in a 3D … and endothelial cells, and requires specific growth factors and …
invasion of cancer cells in a 3D … and endothelial cells, and requires specific growth factors and …
[HTML][HTML] An overview of in vitro, in vivo, and computational techniques for cancer-associated angiogenesis studies
… response have necessitated the development of an alternative … of endothelial cells of the
surrounding tumor tissues. The … between pro- and anti-angiogenic factors. Neovascularization …
surrounding tumor tissues. The … between pro- and anti-angiogenic factors. Neovascularization …